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Research_ArticleResearch Article

Inconclusive Diagnosis of a Lymphoid Neoplasm

Alice Nguyen, Akita Joshi, Samantha Trinh and Sara Taylor
American Society for Clinical Laboratory Science April 2018, ascls.118.000166; DOI: https://doi.org/10.29074/ascls.118.000166
Alice Nguyen
Tarleton State University
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Akita Joshi
Tarleton State University
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Samantha Trinh
Tarleton State University
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Sara Taylor
Tarleton State University
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  1. Alice Nguyen
  2. Akita Joshi
  3. Samantha Trinh
  4. Sara Taylor1
  1. Tarleton State University
  1. ↵* Corresponding author; email: sataylor{at}tarleton.edu

Abstract

OBJECTIVE: This case study outlines the diagnostic schema employed at our facility to accurately identify a patient's hematological condition to facilitate optimal treatment. BACKGROUND: A 71 year old male patient presented to our hospital with complete blood count (CBC) data that was suggestive of a lymphoid malignancy due to a critically low leukocyte count coupled with a predominance of lymphocytes displaying abnormal morphology. METHOD: Immunophenotyping studies carried out on the bone marrow indicated that the patient had a B lymphocyte malignancy, although a T cell neoplasm could not be ruled out. Karyotyping on this patient revealed a complex karyotype which supported the conclusion that this patient suffered from a malignant condition. Finally, molecular diagnostics testing was employed to specifically identify the disease state. CONCLUSION: While the testing results are suggestive of a lymphoid malignancy, the patient's diagnosis remains unclearly defined.

  • Hematology
  • Immunology
  • Lymphoma
  • T Cell Receptor
  • Received February 18, 2018.
  • Accepted February 18, 2018.
  • Published by American Society for Clinical Laboratory Science
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American Society for Clinical Laboratory Science: 30 (4)
American Society for Clinical Laboratory Science
Vol. 30, Issue 4
Fall 2017
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Inconclusive Diagnosis of a Lymphoid Neoplasm
Alice Nguyen, Akita Joshi, Samantha Trinh, Sara Taylor
American Society for Clinical Laboratory Science Apr 2018, ascls.118.000166; DOI: 10.29074/ascls.118.000166

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Inconclusive Diagnosis of a Lymphoid Neoplasm
Alice Nguyen, Akita Joshi, Samantha Trinh, Sara Taylor
American Society for Clinical Laboratory Science Apr 2018, ascls.118.000166; DOI: 10.29074/ascls.118.000166
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Keywords

  • Hematology
  • Immunology
  • Lymphoma
  • T Cell Receptor

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