TY - JOUR T1 - Past, Present and Future Options in the Treatment of Hemophilia A JF - American Society for Clinical Laboratory Science JO - Clin Lab Sci DO - 10.29074/ascls.118.001032 SP - ascls.118.001032 AU - Donna D Castellone Y1 - 2019/01/01 UR - http://hwmaint.clsjournal.ascls.org/content/early/2019/10/26/ascls.118.001032.abstract N2 - Patients who present with hemophilia A require treatment to replace low levels of Factor VIII (FVIII). Intervention can either be on demand or prophylactically. The goal of therapy is to prevent joint bleeds that lead to permanent damage. The progression of therapy in hemophilia A has provided patients with options resulting in a greatly improved quality of life. The newest development of gene therapy, to replace FVIII, may be the answer to cure this disease. This review provides a historical account of the treatment for hemophilia A as well as current available treatment options. ER -