RT Journal Article
SR Electronic
T1 Past, Present, and Future Options in the Treatment of Hemophilia A
JF American Society for Clinical Laboratory Science
JO Clin Lab Sci
FD American Society of Chemistry and Laboratory Science
SP 36
OP 42
DO 10.29074/ascls.2018001032
VO 32
IS 1
A1 Castellone, Donna D.
YR 2019
UL http://hwmaint.clsjournal.ascls.org/content/32/1/36.abstract
AB Patients who present with hemophilia A require treatment to replace low levels of factor VIII (FVIII). Intervention can either be on-demand or prophylactic. The goal of therapy is to prevent joint bleeds that lead to permanent damage. The progression of therapy in hemophilia A has provided patients with options that result in a greatly improved quality of life. The newest development of gene therapy, a replacement for FVIII, may be the answer to cure this disorder. This review provides a historical account of the treatment of hemophilia A as well as current available treatment options.