RT Journal Article
SR Electronic
T1 Hemophilia
JF American Society for Clinical Laboratory Science
JO Clin Lab Sci
FD American Society of Chemistry and Laboratory Science
SP 21
OP 26
DO 10.29074/ascls.2018001289
VO 32
IS 1
A1 Smith, Larry J.
YR 2019
UL http://hwmaint.clsjournal.ascls.org/content/32/1/21.abstract
AB Hemophilia is a rare, congenital bleeding disease with an X-linked recessive inheritance pattern. It is characterized by absent, decreased, or dysfunctional coagulation factor VIII (FVIII) or factor IX (FIX). Individuals with severe hemophilia bleed into the joints, soft tissue, and muscles, which can be debilitating. Although hemophilia is a serious life-long bleeding disease, understanding the pathogenesis of the disease leads to better patient treatment and improved patient outcomes.