Abstract
We describe the first known case of a fatal infection with small colony variants of methicillin-resistant Staphylococcus aureus in a patient with AIDS. Recovered from three blood cultures as well as from a deep hip abscess, these variants may have resulted from long-term antimicrobial therapy with trimethoprim/sulfamethoxazole for prophylaxis of Pneumocystis carinii pneumonia.
MeSH terms
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AIDS-Related Opportunistic Infections / drug therapy*
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AIDS-Related Opportunistic Infections / microbiology
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Abscess / drug therapy
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Abscess / microbiology
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Adult
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Bacteremia / drug therapy
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Bacteremia / microbiology
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Fatal Outcome
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Hip
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Humans
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Male
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Methicillin Resistance*
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Osteomyelitis / drug therapy
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Osteomyelitis / microbiology
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Polymorphism, Genetic
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Staphylococcal Infections / drug therapy*
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Staphylococcal Infections / microbiology
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Staphylococcus aureus / drug effects*
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Staphylococcus aureus / genetics*
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Staphylococcus aureus / growth & development