Lipid–Peptide Vesicle Nanoscale Hybrids for Triggered Drug Release by Mild Hyperthermia in Vitro and in Vivo
…, WT Al-Jamal, JV Bossche, TT Bui, AF Drake… - ACS …, 2012 - ACS Publications
The present study describes leucine zipper peptide–lipid hybrid nanoscale vesicles engineered
by self-assembled anchoring of the amphiphilic peptide within the lipid bilayer. These …
by self-assembled anchoring of the amphiphilic peptide within the lipid bilayer. These …
Fate of silica nanoparticles in simulated primary wastewater treatment
…, MJ Bowes, MJ Lawrence, AF Drake… - Environmental …, 2009 - ACS Publications
Through novel application of small-angle neutron scattering, we examined the fate of silica
nanoparticles (SiO 2 NPs) during simulated primary wastewater treatment, by measuring, in …
nanoparticles (SiO 2 NPs) during simulated primary wastewater treatment, by measuring, in …
The importance of extended conformations and, in particular, the PII conformation for the molecular recognition of peptides
G Siligardi, AF Drake - Biopolymers: Original Research on …, 1995 - Wiley Online Library
Crystallographic, isotopic labeling nmr and transferred nuclear Overhauser effect studies have
highlighted the extended conformation as a very important element of secondary structure …
highlighted the extended conformation as a very important element of secondary structure …
Reassessment of the electronic circular dichroism criteria for random coil conformations of poly (L-lysine) and the implications for protein folding and denaturation …
AF Drake, G Siligardi, WA Gibbons - Biophysical chemistry, 1988 - Elsevier
The circular dichroism (CD) spectra of poly(l-lysine) in water and ethanediol/water (2:1)
solutions in the temperature range − 110 to 85C are presented. The results combined with …
solutions in the temperature range − 110 to 85C are presented. The results combined with …
Enzymatically cross-linked tilapia gelatin hydrogels: physical, chemical, and hybrid networks
F Bode, MA Da Silva, AF Drake… - …, 2011 - ACS Publications
This Article investigates different types of networks formed from tilapia fish gelatin (10% w/w)
in the presence and absence of the enzymatic cross-linker microbial transglutaminase. The …
in the presence and absence of the enzymatic cross-linker microbial transglutaminase. The …
Polarisation modulation-the measurement of linear and circular dichroism
AF Drake - Journal of Physics E: Scientific Instruments, 1986 - iopscience.iop.org
Dichroism is usually measured using two separate polarisation spectra. However, when the
difference in the transmission of oppositely polarised light is very small, the superior method …
difference in the transmission of oppositely polarised light is very small, the superior method …
Characterization of protein aggregation: the case of a therapeutic immunoglobulin
B Demeule, MJ Lawrence, AF Drake, R Gurny… - … et Biophysica Acta (BBA …, 2007 - Elsevier
In this paper, a therapeutic immunoglobulin (Antibody A) has been characterized in two
solutions: (1) 0.1% acetic acid containing 50 mM magnesium chloride, a solution in which the …
solutions: (1) 0.1% acetic acid containing 50 mM magnesium chloride, a solution in which the …
Amyloid β-peptide 25–35 self-assembly and its inhibition: A model undecapeptide system to gain atomistic and secondary structure details of the Alzheimer's disease …
M Naldi, J Fiori, M Pistolozzi, AF Drake… - ACS chemical …, 2012 - ACS Publications
Combined results of theoretical molecular dynamic simulations and in vitro spectroscopic (circular
dichroism and fluorescence) studies are presented, providing the atomistic and …
dichroism and fluorescence) studies are presented, providing the atomistic and …
[HTML][HTML] Conformational flexibility determines selectivity and antibacterial, antiplasmodial, and anticancer potency of cationic α-helical peptides
…, RA Atkinson, JKW Lam, SS Bansal, AF Drake… - Journal of Biological …, 2012 - ASBMB
We used a combination of fluorescence, circular dichroism (CD), and NMR spectroscopies in
conjunction with size exclusion chromatography to help rationalize the relative antibacterial…
conjunction with size exclusion chromatography to help rationalize the relative antibacterial…
[HTML][HTML] Undervalued and ignored: Are humans poorly adapted to energy-dense foods?
In many species the capacity to accurately differentiate the energy density (kcal/g) of foods
is critical because it greatly improves efficiency in foraging. In modern humans this ability …
is critical because it greatly improves efficiency in foraging. In modern humans this ability …