User profiles for Alex Rai
Alex J. RaiProfessor and Director, Clinical Chemistry Service; co-Director Automated Core Laboratory Verified email at cumc.columbia.edu Cited by 6551 |
Three biomarkers identified from serum proteomic analysis for the detection of early stage ovarian cancer
Early detection remains the most promising approach to improve long-term survival of
patients with ovarian cancer. In a five-center case-control study, serum proteomic expressions …
patients with ovarian cancer. In a five-center case-control study, serum proteomic expressions …
Circulating tumor DNA analysis in patients with cancer: American Society of Clinical Oncology and College of American Pathologists joint review
Purpose.— Clinical use of analytical tests to assess genomic variants in circulating tumor
DNA (ctDNA) is increasing. This joint review from the American Society of Clinical Oncology …
DNA (ctDNA) is increasing. This joint review from the American Society of Clinical Oncology …
Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core …
HUPO initiated the Plasma Proteome Project (PPP) in 2002. Its pilot phase has (1) evaluated
advantages and limitations of many depletion, fractionation, and MS technology platforms; (…
advantages and limitations of many depletion, fractionation, and MS technology platforms; (…
HUPO Plasma Proteome Project specimen collection and handling: towards the standardization of parameters for plasma proteome samples
AJ Rai, CA Gelfand, BC Haywood, DJ Warunek… - …, 2005 - Wiley Online Library
There is a substantial list of pre‐analytical variables that can alter the analysis of blood‐derived
samples. We have undertaken studies on some of these issues including choice of …
samples. We have undertaken studies on some of these issues including choice of …
A smartphone dongle for diagnosis of infectious diseases at the point of care
…, E Munyazesa, P Mugwaneza, AJ Rai… - Science translational …, 2015 - science.org
This work demonstrates that a full laboratory-quality immunoassay can be run on a
smartphone accessory. This low-cost dongle replicates all mechanical, optical, and electronic …
smartphone accessory. This low-cost dongle replicates all mechanical, optical, and electronic …
Proteomic approaches to tumor marker discovery: identification of biomarkers for ovarian cancer
Context.—Current tumor markers for ovarian cancer still lack adequate sensitivity and
specificity to be applicable in large populations. High-throughput proteomic profiling and …
specificity to be applicable in large populations. High-throughput proteomic profiling and …
[HTML][HTML] Serum mesothelin for diagnosing malignant pleural mesothelioma: an individual patient data meta-analysis
Purpose Mesothelin is currently considered the best available serum biomarker of malignant
pleural mesothelioma. To examine the diagnostic accuracy and use of serum mesothelin in …
pleural mesothelioma. To examine the diagnostic accuracy and use of serum mesothelin in …
Molecular biomarkers in localized prostate cancer: ASCO guideline
…, T van der Kwast, DJ Grignon, AJ Rai… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE This guideline provides recommendations for available tissue-based prostate
cancer biomarkers geared toward patient selection for active surveillance, identification of …
cancer biomarkers geared toward patient selection for active surveillance, identification of …
Types of assays for SARS-CoV-2 testing: a review
…, SL Spitalnik, EA Hod, AJ Rai - Laboratory …, 2020 - academic.oup.com
Clinical laboratory testing routinely provides actionable results, which help direct patient
care in the inpatient and outpatient settings. Since December 2019, a novel coronavirus (SARS-…
care in the inpatient and outpatient settings. Since December 2019, a novel coronavirus (SARS-…
Effects of preanalytical variables on peptide and protein measurements in human serum and plasma: implications for clinical proteomics
AJ Rai, F Vitzthum - Expert review of proteomics, 2006 - Taylor & Francis
There is a wealth of knowledge in the field of in vitro diagnostics with regard to preanalytical
variables and their impact on the determination of peptide and protein analytes in human …
variables and their impact on the determination of peptide and protein analytes in human …