Background In the European Organization for Research and Treatment of Cancer (EORTC)
randomized trial 30904, nephron-sparing surgery (NSS) was associated with reduced …

BACKGROUD: Sex, race, and age at diagnosis have a significant impact on mortality from
bladder cancer (BC). Women, African Americans of both sexes, and the elderly, all experience …

BACKGROUND: The objectives of this study were to determine the frequency of metastatic (M1)
prostate cancer (PC) at presentation in different age groups, to examine the association …

Study Type – Therapy (RCT) Level of Evidence 1b What's known on the subject? and What
does the study add? In a meta‐analysis of randomized trials, neoadjuvant platinum‐based …

OBJECTIVES: To determine whether the survival of patients with squamous cell carcinoma (SCC)
is different from that of patients with urothelial carcinoma, after adjusting for stage, …

The Surveillance, Epidemiology, and End Results (SEER) program is a commonly used
data source in cancer research. This article provides an introduction to the SEER database, …

Background Rett syndrome is a rare, severe neurodevelopmental disorder. Almost all cases
occur in girls, in association with spontaneous (non-inherited) mutations involving the methyl…

Clinical trials usually do not have the power to detect rare adverse drug reactions. Spontaneous
adverse reaction reports as for example available in post-marketing safety databases …

Background Many patients with chronic spontaneous urticaria (CSU) do not achieve complete
control of their symptoms with current available treatments. In a dose-finding phase 2b …

Objectives In the United States, among patients diagnosed with bladder cancer (BC), women
have increased disease-specific mortality compared with men. The main objective of this …