Wire delay is emerging as the natural limiter to microprocessor scalability. A new architectural
approach could solve this problem, as well as deliver unprecedented performance, energy …

Long-read single-molecule sequencing has revolutionized de novo genome assembly and
enabled the automated reconstruction of reference-quality genomes. However, given the …

As next-generation sequencing projects generate massive genome-wide sequence variation
data, bioinformatics tools are being developed to provide computational predictions on the …

The emergence of next-generation sequencing platforms led to resurgence of research in
whole-genome shotgun assembly algorithms and software. DNA sequencing data from the …

CRISPR/Cas is a revolutionary gene editing technology with wide‐ranging utility. The safe,
non‐viral delivery of CRISPR/Cas components would greatly improve future therapeutic utility…

Anopheles gambiae is the principal vector of malaria, a disease that afflicts more than 500
million people and causes more than 1 million deaths each year. Tenfold shotgun sequence …

We present a draft sequence of the genome of Aedes aegypti, the primary vector for yellow
fever and dengue fever, which at ∼1376 million base pairs is about 5 times the size of the …

The whole-genome duplication 80 million years ago of the common ancestor of salmonids (salmonid-specific
fourth vertebrate whole-genome duplication, Ss4R) provides unique …

This paper evaluates the Raw microprocessor. Raw addresses thechallenge of building a
general-purpose architecture that performswell on a larger class of stream and embedded …

The human microbiome refers to the community of microorganisms, including prokaryotes,
viruses, and microbial eukaryotes, that populate the human body. The National Institutes of …