Although nicotinic agonists can modulate sensory transmission, particularly nociceptive
signaling, remarkably little is known about the functional expression of nicotinic acetylcholine …

Objectives To provide a clinical laboratory perspective on the Verifying Accurate Leading-edge
IVCT Development Act (VALID) discussion draft. This potential legislative effort, if enacted…

In total laboratory automation (TLA) 10, preanalytic, analytic, and postanalytic phases of
laboratory testing may be combined into an integrated system such that specimens are …

BACKGROUND Twenty-five years ago, the Food and Drug Administration (FDA) asserted in
a draft document that “home brew” tests—now commonly referred to as laboratory-…

Among the most important functions of a pathology or laboratory medicine service is the
clear, accurate, and rapid communication of critical test results (critical values) to patient care …

Context.— Serum tests used for the screening and diagnosis of monoclonal gammopathies
include serum protein electrophoresis (SPE; agarose gel or capillary zone), immunofixation (…

Macrophages can fuse to form osteoclasts in bone or multinucleate giant cells (MGCs) as
part of the immune response. We use a systems genetics approach in rat macrophages to …

Urine drug screens are commonly performed to identify drug use or monitor adherence to
drug therapy. The purpose of this retrospective study was to evaluate the true positive and …

Methods| In March 2022, the College of American Pathologists distributed an optional 5-question
survey to clinical laboratories that participated in the first general chemistry proficiency …

Purpose.‐Quality of life evaluations can enhance traditional measures of therapeutic efficacy.
The purpose of our study was to evaluate the impact of sumatriptan on the quality of life of …