Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-19

…, LTJ Hickson, JC O'Horo, JB Hoyne… - Science translational …, 2021 - science.org
Brain imaging studies of patients with COVID-19 show evidence of macro- and microhemorrhagic
lesions, multifocal white matter hyperintensities, and lesions consistent with posterior …

Accuracy of calculated free testosterone differs between equations and depends on gender and SHBG concentration

JS Hackbarth, JB Hoyne, SK Grebe, RJ Singh - Steroids, 2011 - Elsevier
Serum free testosterone (fT) concentrations are often calculated, however different equations
often yield discrepant results. This study explores the sources of this variability. We …

Deep vein thrombosis and pulmonary embolism among hospitalized coronavirus disease 2019–positive patients predicted for higher mortality and prolonged …

…, T Gendron, R McBane, M Park, JB Hoyne… - Journal of Vascular …, 2021 - Elsevier
Objective We assessed the incidence of deep vein thrombosis (DVT) and pulmonary embolism
(PE) in hospitalized patients with coronavirus disease 2019 (COVID-19) compared with …

Early absent pupillary light reflexes after cardiac arrest in patients treated with therapeutic hypothermia

…, B Rawal, MG Heckman, JB Hoyne… - Therapeutic …, 2016 - liebertpub.com
Loss of pupillary light reactivity is one recognized indicator of poor prognosis after
cardiopulmonary resuscitation (CPR). However, drug overdose, low cardiac output, and/or …

Evidence that the APOE locus influences rate of disease progression in late onset familial Alzheimer's disease but is not causative

…, A Osborne, P Diaz, J Hoyne… - American journal of …, 1995 - Wiley Online Library
An association has been observed in several independent data sets between late onset
Alzheimer's Disease (AD) and the APOE locus on chromosome 19. We have examined the …

High-sensitivity troponin T and NT-proBNP kinetics in breast cancer chemotherapy

P Advani, J Hoyne, A Moreno-Aspita, M Dubin… - Chemotherapy, 2017 - karger.com
Background/Aims: Doxorubicin (DOX) and trastuzumab (TRA) are associated with cardiac
dysfunction. Method: High-sensitivity troponin T (hs-TnT) and brain natriuretic peptide …

[PDF][PDF] Neurofilament light chain and vaccination status associate with clinical outcomes in severe COVID-19

…, B Oskarsson, KA Nicholson, ZK Wszolek, JB Hoyne… - IScience, 2022 - cell.com
Blood neurofilament light chain (NFL) is proposed to serve as an estimate of disease severity
in hospitalized patients with coronavirus disease 2019 (COVID-19). We show that NFL …

No association between the intronic presenilin‐1 polymorphism and Alzheimer's disease in clinic and population‐based samples

X Cai, J Stanton, D Fallin, J Hoyne… - American journal of …, 1997 - Wiley Online Library
Mutations in the Presenilin 1 (PS1) gene on chromosome 14 cause most early-onset familial
Alzheimer's disease (AD). An intronic polymorphism in the PSI gene was recently identified …

Dopamine DRD2/Cys311 is not associated with chronic schizophrenia

F Crawford, J Hoyne, X Cai, A Osborne… - American journal of …, 1996 - Wiley Online Library
A mutation in the DRD2 receptor gene has been reported in association with schizophrenia
in Japanese and Caucasian populations. The variation, Ser to Cys at codon 311, occurs in …

Familial and population-based studies of apolipoprotein E and Alzheimer's disease.

…, D Fallin, M Gold, J Schinka, J Hoyne… - Annals of the New …, 1996 - europepmc.org
The finding of an association between the epsilon 4 allele of the APOE locus and the early
expression of late-onset Alzheimer's disease (AD) is robust. However, the estimates of the …