Chimeric antigen receptor T-cells (CAR-T) are now a standard approach for treating
relapsed/refractory B-cell lymphomas. Immune effector cell-associated hemophagocytic …

Morphologic features of myelodysplastic syndromes (MDSs) are well-characterized in
peripheral blood (PB) and bone marrow (BM); however, the specificity and sensitivity of PB …

Platelet function testing serves to detect intrinsic or acquired platelet dysfunction, and may
be used to monitor the therapeutic effect of antiplatelet drugs. The PFA-100 system (Siemens) …

With the increasing use of direct thrombin inhibitors (DTIs) in patients with complex medical
problems, it is important to recognize the effects of these medications on routine coagulation …

Factor VIII (FVIII) levels are subject to many preanalytic variables, including inappropriate
processing and acute phase reaction. Having identified preanalytic issues causing falsely low …

Refractory anemia with excess blasts (RAEB) is a high-grade myelodysplastic syndrome (MDS).
Per 2008 WHO adult criteria, presence of Auer rods in blasts qualifies a case as RAEB-2…

Objectives Evaluation of light chain restriction is critical to establish clonality in B-cell
lymphoproliferative disorders (LPDs). Immunohistochemistry (IHC) and in situ hybridization (ISH) …

A 56-year-old man presented for hematology consultation after splenomegaly (16 cm) was
incidentally discovered on CT urogram. Laboratory evaluation was significant for mild …

Three patients were diagnosed at our facility with therapy-related acute myeloid leukemia (t-AML)
but had differing etiologies. Patient A was a 30-year-old male with a history of acute …

Peripheral blood (PB)-reactive monocytosis is associated with infection, neutropenia,
autoimmunity, and some neoplasms. However, little is known regarding clinicopathologic features …