Along the Texas–Mexico border, the prevalence of neural tube defects (NTDs) among
Mexican-American women doubled during 1990–1991. The human outbreak began during the …

Background: Amine-containing (nitrosatable) drugs can react with nitrite to form N-nitroso
compounds, some of which are teratogenic. Data are lacking on whether dietary intake of …

Arsenic, cadmium, lead, and mercury are neurotoxins, and some studies suggest that these
elements might also be teratogens. Using a case–control study design, we investigated the …

PURPOSE: The relation between maternal pesticide exposures and neural tube defects (NTDs)
in offspring was evaluated in 184 Mexican American case-women and 225 comparison …

Objectives Cigarettes, alcoholic beverages, and street drugs contain substances potentially
toxic to the developing embryo. We investigated whether maternal cigarette smoking, …

BACKGROUND Hyperthermia produces neural tube defects (NTDs) in a variety of animal
species. Elevated maternal body temperatures may also place the developing human embryo …

PURPOSE: Neural tube defects (NTDs) are common birth defects that can be prevented with
folate fortification and supplementation. Studies suggest that other nutrients may also be …

We reviewed the published findings from the Texas Neural Tube Defect Project, a 6‐year
case‐control study (1995–2000) of neural tube defects (NTDs) on the Texas‐Mexico border. In …

BACKGROUND Although cigarette smoke is a well‐established toxin and harmful to the
developing embryo, the evidence for an independent effect on the occurrence of neural tube …

BACKGROUND: To better understand the neural tube defect (NTD) causal pathway, the
authors measured homocysteine, an indicator of tissue micronutrient deficiencies. The authors …