Sophorolipids and their derivatives are lethal against human pancreatic cancer cells

…, MD Hagler, ME Zenilman, R Gross, MH Bluth - Journal of surgical …, 2008 - Elsevier
INTRODUCTION: We have previously demonstrated that sophorolipids, a class of easily
chemoenzymatically modifiable glycolipids, possess anti-inflammatory effects in vitro and in vivo…

Interleukin-33-induced expression of PIBF1 by decidual B cells protects against preterm labor

…, C Shen, LA Polin, RA Nichols, TB Jones, MH Bluth… - Nature medicine, 2017 - nature.com
Preterm birth (PTB) is a leading cause of neonatal death worldwide 1 . Intrauterine and systemic
infection and inflammation cause 30–40% of spontaneous preterm labor (PTL) 2 , which …

Sophorolipids block lethal effects of septic shock in rats in a cecal ligation and puncture model of experimental sepsis

MH Bluth, E Kandil, CM Mueller, V Shah… - Critical care …, 2006 - journals.lww.com
Objective: Sophorolipids, a family of natural and easily chemoenzymatically modified
microbial glycolipids, are promising modulators of the immune response. The potential of the …

Pharmacogenomics of drug metabolizing enzymes and transporters: implications for cancer therapy

J Li, MH Bluth - Pharmacogenomics and personalized medicine, 2011 - Taylor & Francis
The new era of personalized medicine, which integrates the uniqueness of an individual
with respect to the pharmacokinetics and pharmacodynamics of a drug, holds promise as a …

Sophorolipids improve sepsis survival: effects of dosing and derivatives

…, M Nowakowski, ME Zenilman, MH Bluth - Journal of Surgical …, 2007 - Elsevier
INTRODUCTION: Sophorolipids, a family of natural and easily chemo-enzymatically
modified microbial glycolipids, are promising modulators of the immune response. We have …

Corynebacterium urealyticum: a comprehensive review of an understated organism

…, L Salem, S Saber, G Ismail, MH Bluth - Infection and drug …, 2015 - Taylor & Francis
Corynebacterium urealyticum is a Gram positive, slow-growing, lipophilic, multi-drug resistant,
urease positive micro-organism with diphtheroid morphology. It has been reported as an …

B-type natriuretic peptide: a biomarker for the diagnosis and risk stratification of patients with septic shock

…, A Schwartzman, ME Zenilman, MH Bluth - Archives of …, 2008 - jamanetwork.com
Background The importance of cardiomyocyte damage during sepsis has been a recent
subject of interest. The progression of sepsis results in the upregulation of proinflammatory …

Hemolytic transfusion reactions

RD Davenport, MH Bluth - Rossi's principles of transfusion …, 2016 - Wiley Online Library
A hemolytic transfusion reaction (HTR) is destruction of red cells due to immunologic
incompatibility between the donor and recipient. While current stringent compatibility testing and …

Sophorolipids as antibacterial agents

…, ME Zenilman, MH Bluth - Annals of Clinical & …, 2009 - Assoc Clin Scientists
… Address correspondence to Martin H. Bluth, MD, Ph.D, Department of Pathology, 8203 Scott
Hall, Wayne State University School of Medicine, 540 E. Canfield, Detroit, MI 48201, USA; …

Molecular diagnostics in colorectal carcinoma: advances and applications for 2018

A Bhalla, M Zulfiqar, MH Bluth - Clinics in laboratory …, 2018 - labmed.theclinics.com
The pathogenesis of colorectal carcinoma is heterogeneous and involves complex multistep
molecular pathways initiated by genetic and epigenetic events. The molecular classification …