Multiple sclerosis is a complex neurological disease, with ∼20% of risk heritability attributable
to common genetic variants, including >230 identified by genome-wide association …

Objectives The clinical course of multiple sclerosis (MS) is highly variable, and research
data collection is costly and time consuming. We evaluated natural language processing …

T HE WORKSITE HAS BECOME the target of numerous groups seeking to improve the health
of the adult population. In 1979, the Public Health Service's Office of Health Information …

Electronic medical records (EMRs) are being quickly adopted in clinics around the world.
This advancement can greatly enhance the clinical care of patients with multiple sclerosis (MS) …

IAP is a glycoprotein functionally and physically associated with some integrins, ie, the
leukocyte response integrin and the beta3 integrin chain on placenta, platelets, and …

Successful delivery of promising new chemical entities via the oral route is rife with
challenges, some of which cannot be explained or foreseen during drug development. Further …

Background: Despite the well-known recidivism of obesity, surprisingly little is known about
the composition of body weight during weight regain. Objective: The objective of this study …

Low-frequency coding DNA sequence variants in the proprotein convertase subtilisin/kexin
type 9 gene (PCSK9) lower plasma low-density lipoprotein cholesterol (LDL-C), protect …

Previous investigations of solid organ transplant patients treated with tacrolimus showed
that individuals carrying a CYP3A5*1 allele have lower dose-adjusted trough blood …

Genome-wide association studies have identified 32 loci influencing body mass index, but
this measure does not distinguish lean from fat mass. To identify adiposity loci, we meta-…