User profiles for Richard Y Zhao

Richard Y. Zhao

University of Maryland School of Medicine
Verified email at som.umaryland.edu
Cited by 4544

Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention

…, KW Weitzel, RA Wilke, J Willig, RY Zhao… - JACC: Cardiovascular …, 2018 - jacc.org
Objectives : This multicenter pragmatic investigation assessed outcomes following clinical
implementation of CYP2C19 genotype–guided antiplatelet therapy after percutaneous …

[HTML][HTML] Understanding the role of SARS-CoV-2 ORF3a in viral pathogenesis and COVID-19

…, M Nasr, Q Tang, JM Simard, RY Zhao - Frontiers in …, 2022 - frontiersin.org
The ongoing SARS-CoV-2 pandemic has shocked the world due to its persistence, COVID-19-related
morbidity and mortality, and the high mutability of the virus. One of the major …

[HTML][HTML] Guidelines and recommendations on yeast cell death nomenclature

…, S Wissing, S Woelfl, ZJ Zhang, RY Zhao… - Microbial Cell, 2018 - ncbi.nlm.nih.gov
Elucidating the biology of yeast in its full complexity has major implications for science, medicine
and industry. One of the most critical processes determining yeast life and physiology is …

[HTML][HTML] Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions

L Li, HS Li, CD Pauza, M Bukrinsky, RY Zhao - Cell research, 2005 - nature.com
Active host-pathogen interactions take place during infection of human immunodeficiency
virus type 1 (HIV-1). Outcomes of these interactions determine the efficiency of viral infection …

Up-regulation of 14-3-3ζ in lung cancer and its implication as prognostic and therapeutic target

…, NW Todd, Q Qiu, HB Fang, H Wang, J Shen, RY Zhao… - Cancer research, 2007 - AACR
A functional genomic approach integrating microarray and proteomic analyses done in our
laboratory has identified 14-3-3ζ as a putative oncogene whose activation was common and …

Implementation of pharmacogenetics: The University of Maryland personalized anti‐platelet pharmacogenetics program

…, L Brown, LJB Jeng, RY Zhao… - American Journal of …, 2014 - Wiley Online Library
Despite a substantial evidence base, implementation of pharmacogenetics into routine patient
care has been slow due to a number of non‐trivial practical barriers. We implemented a …

[HTML][HTML] Viral infections and cell cycle G2/M regulation

RY Zhao, RT Elder - Cell research, 2005 - nature.com
Progression of cells from G2 phase of the cell cycle to mitosis is a tightly regulated cellular
process that requires activation of the Cdc2 kinase, which determines onset of mitosis in all …

Blinded, multicenter comparison of methods to detect a drug-resistant mutant of human immunodeficiency virus type 1 at low frequency

…, S Palmer, R Ziermann, RY Zhao… - Journal of clinical …, 2006 - Am Soc Microbiol
We determined the abilities of 10 technologies to detect and quantify a common drug-resistant
mutant of human immunodeficiency virus type 1 (lysine to asparagine at codon 103 of the …

Genetic Deletions in Sputum as Diagnostic Markers for Early Detection of Stage I Non–Small Cell Lung Cancer

R Li, NW Todd, Q Qiu, T Fan, RY Zhao… - Clinical cancer …, 2007 - AACR
Purpose: Analysis of molecular genetic markers in biological fluids has been proposed as a
powerful tool for cancer diagnosis. We have characterized in detail the genetic signatures in …

Characterization of cytopathic factors through genome-wide analysis of the Zika viral proteins in fission yeast

…, JM Simard, RC Gallo, RY Zhao - Proceedings of the …, 2017 - National Acad Sciences
The Zika virus (ZIKV) causes microcephaly and the Guillain-Barré syndrome. Little is known
about how ZIKV causes these conditions or which ZIKV viral protein(s) is responsible for the …