[HTML][HTML] Impact of antivenom administration on the evolution of cutaneous lesions in loxoscelism: A prospective observational study

CMS Malaque, CTG Novaes, RO Piorelli… - PLoS Neglected …, 2022 - journals.plos.org
Background Spiders of the genus Loxosceles are distributed throughout tropical and
temperate regions worldwide. Loxosceles spp. bites may evolve to necrosis, with or without …

Venomous animals: clinical toxinology

J White - … , Clinical and Environmental Toxicology: Volume 2 …, 2010 - Springer
Venomous animals occur in numerous phyla and present a great diversity of taxa, toxins,
targets, clinical effects and outcomes. Venomous snakes are the most medically significant …

Sphingomyelinases in a journey to combat arthropod‐borne pathogen transmission

KV Rajendran, G Neelakanta, H Sultana - FEBS letters, 2021 - Wiley Online Library
Ixodes scapularis ticks feed on humans and other vertebrate hosts and transmit several
pathogens of public health concern. Tick saliva is a complex mixture of bioactive proteins …

Clinical picture and laboratorial evaluation in human loxoscelism

CMS Malaque, ML Santoro, JLC Cardoso, MR Conde… - Toxicon, 2011 - Elsevier
Loxosceles spiders are found globally, especially in South and North America. In Brazil,
approximately 10,000 cases of Loxosceles spp. spider bites are reported annually. Herein …

[HTML][HTML] Rhipicephalus (Boophilus) microplus: clotting time in tick-infested skin varies according to local inflammation and gene expression patterns in tick salivary …

WA Carvalho, SR Maruyama, AM Franzin… - Experimental …, 2010 - Elsevier
Ticks deposit saliva at the site of their attachment to a host in order to inhibit haemostasis,
inflammation and innate and adaptive immune responses. The anti-haemostatic properties …

Biochemical characterization of a novel sphingomyelinase-like protein from the Rhipicephalus microplus tick

FAA Silva, GCA Costa, LF Parizi, ISV Junior… - Experimental …, 2023 - Elsevier
Sphingomyelinase D is a toxin present in venomous spiders and bacteria and is associated
with infection symptoms in patients affected by spider bites. It was observed that in Ixodes …

Loxoscelism and negative pressure wound therapy (vacuum‐assisted closure): an experimental study

SL Wong, AM Schneider, LC Argenta… - International Wound …, 2010 - Wiley Online Library
Brown recluse spider (Loxosceles) bites cause lesions ranging from chronic necrotic ulcers
to acute life‐threatening sepsis. Based on our experience in treating acute and chronic …

[HTML][HTML] Comparative treatment with hyperbaric oxygen therapy in a model of systemic loxoscelism in rats

M Toledo-Blas, A Franco-Vadillo… - Iranian Journal of …, 2022 - ncbi.nlm.nih.gov
Objective (s): Spiders of the Loxosceles genus, known as violin spiders, produce venom with
dermonecrotic and systemic effects, as it is a species widely distributed in the world, its study …

[HTML][HTML] Heterophilic antibodies in sera from individuals without loxoscelism cross-react with phospholipase D from the venom of Loxosceles and Sicarius spiders

T Arán-Sekul, JM Rojas, M Subiabre, V Cruz… - Journal of Venomous …, 2018 - SciELO Brasil
Background Loxoscelism is a severe human envenomation caused by Loxosceles spider
venom. To the best of our knowledge, no study has evaluated the presence of antibodies …

'Partitagin', a unique β, γ-fibrinogenase that inhibits platelet aggregation from Hippasa partita spider venom

N Shivaiah, K Kempaiah - Blood coagulation & fibrinolysis, 2011 - journals.lww.com
Abstract Partitagin, a Zn 2+-containing hemorrhagic metalloprotease from Hippasa partita
spider venom gland extract has been purified and studied for its dermonecrotic and …