Von Willebrand disease (VWD) constitutes the most common inherited human bleeding
disorder. It is associated with a mucocutaneous bleeding phenotype that can significantly …

ABSTRACT von Willebrand disease (VWD) is the most common inherited bleeding disorder
and arises from deficiencies and/or defects in the plasma protein von Willebrand factor …

Introduction von Willebrand disease (VWD), reportedly the most common bleeding disorder,
arises from deficiency and/or defects of von Willebrand factor (VWF). Assessment requires a …

The ristocetin cofactor assay (VWF: RCo) is the reference method for assessing von
Willebrand factor (VWF) activity in the diagnosis of von Willebrand's Disease (VWD) …

Hemostasis is traditionally defined as the physiologic process whereby bleeding is
antagonized and possibly stopped to minimize blood loss. The first medical description of …

von Willebrand factor (VWF) represents a large and complex adhesive plasma protein
whose main function is to provide a bridge between blood platelets and damaged …

Increased awareness of von Willebrand Disease (VWD) has led to more frequent diagnostic
laboratory testing, which insurers often dictate be performed at a facility with off‐site …

von Willebrand factor (VWF) ristocetin cofactor activity (VWF: RCo) by platelet aggregometry
has been considered the gold standard for evaluating the ability of VWF to bind platelets for …

Sažetak The essential elements of a quality program, specifically internal quality control
(IQC) and external quality assurance (EQA), should be applied to each laboratory assay …

The platelet function analyser (PFA‐100) is a biological tool designed to explore primary
haemostasis. This system has thus been widely demonstrated as reliable in detecting von …