Thrombotic Thrombocytopenia Pupura (TTP) is a disease that is classified by abnormal
functioning of the ADAMTS13 protease. ADAMTS13 protease impairment can be caused by …

Thrombotic thrombocytopenic purpura (TTP) is a severe disease associated with unusually
large, hemostatically hyperactive von Willebrand factor (VWF) and severe deficiency in …

The discovery of the important role of the von Willebrand factor (VWF)-cleaving protease
(ADAMTS13) in the etiology and pathogenesis of thrombotic thrombocytopenic purpura …

Acquired thrombotic thrombocytopenia purpura (aTTP) is caused by autoantibody-mediated
severe deficiency of the von Willebrand factor (vWF) cleaving protease ADAMTS13 (a …

The recent discovery of the von Willebrand Factor (vWF) cleaving protease (ADAMTS13)
and the association of its deficiency with thrombotic thrombocytopaenic purpura (TTP) has …

Sažetak Thrombotic thrombocytopenic purpura (TTP) is a disorder characterized by
disseminated thrombotic occlusions of the microcirculation. Identification of ADAMTS13 …

We first summarize the course from the initial description of a patient with thrombotic
thrombocytopenic purpura (TTP) and the creation of the disease's name to the diagnostic …

Abstract Almost 80 years after Eli Moschcowitz published the first description of the disease,
most patients with idiopathic thrombotic thrombocytopenic purpura (TTP) were found to have …

Pathogenesis of thrombotic thrombocytopenic purpura (TTP) was a mystery for over half a
century until the discovery of ADAMTS13. ADAMTS13 is primarily synthesized in the liver …

Introduction Severe ADAMTS13 deficiency defines thrombotic thrombocytopenic purpura
(TTP). ADAMTS13 is responsible for VWF cleavage. In the absence of this enzyme …