Application of Bioinformatic Tools for the Identification and Characterization of Microbes in the Medical Microbiology Laboratory

D Golemboski - American Society for Clinical Laboratory …, 2015 - clsjournal.ascls.org
Genome sequencing technologies have provided information that enables a faster, more
precise characterization of bacteria, according to DNA and RNA sequences. Additionally …

Bacterial genomics in infectious disease and the clinical pathology laboratory

RJ Olsen, SW Long, JM Musser - Archives of pathology & …, 2012 - meridian.allenpress.com
Context.—Throughout history, technologic advancements have fueled the engine of
innovation, which, in turn, has driven discovery. Accordingly, recent advancements in DNA …

Genomic analysis of microbial infections

PM Thwe, P Ren, M Loeffelholz - Molecular Medical Microbiology, 2024 - Elsevier
The genomic analysis of microbial infections entails the use of molecular methods to detect
pathogen-specific genetic sequences to diagnose, monitor, or prognose infections (such as …

Genomics and computational molecular biology

DL Brutlag - Current Opinion in Microbiology, 1998 - Elsevier
There has been a dramatic increase in the number of completely sequenced bacterial
genomes during the past two years as a result of the efforts both of public genome agencies …

Clinical microbiology informatics

DD Rhoads, V Sintchenko, CA Rauch… - Clinical microbiology …, 2014 - Am Soc Microbiol
The clinical microbiology laboratory has responsibilities ranging from characterizing the
causative agent in a patient's infection to helping detect global disease outbreaks. All of …

Genome sequencing and annotation: an overview

M Kuroda, K Hiramatsu - … , and Clinical Bacteriology: Methods and Reviews, 2004 - Springer
Many microbial genome sequences have been determined, and more new genome projects
are ongoing. Shotgun sequencing of randomly cloned short pieces of genomic DNA can …

Bioinformatics of microbial sequences

P Giffard - Infectious Disease Informatics, 2010 - Springer
The pioneering work of Carl Woese demonstrated that comparison of biological sequences
is the key to inferring evolutionary relationships and population structures in the microbial …

BIBI, a bioinformatics bacterial identification tool

G Devulder, G Perriere, F Baty… - Journal of clinical …, 2003 - Am Soc Microbiol
ABSTRACT BIBI was designed to automate DNA sequence analysis for bacterial
identification in the clinical field. BIBI relies on the use of BLAST and CLUSTAL W programs …

Bioinformatics Methods for Microbial Detection and Forensic Diagnostic Design

TR Slezak, SL Salzberg - Microbial Forensics, 2005 - Elsevier
Publisher Summary This chapter reviews bioinformatics techniques that are used for the
detection and identication of microbial samples, and for further analysis of sequence …

Molecular methods in diagnostic microbiology

S Hinrichs, J Wisecarver - Clinics in Laboratory Medicine, 2003 - labmed.theclinics.com
The development of molecular amplification technologies such as polymerase chain
reaction in the mid-1980s provided powerful new tools for detection and identification of …