Each year the United States population receives an estimated 12 to 14 million units of
packed red blood cells (RBCs) and whole blood. 1, 2 It is estimated that 33% of transfusions …

Red blood cell (RBC) transfusions are an important clinical intervention. However, RBC
express hundreds of non-ABO antigens making alloimmunization a significant risk. RhD …

The small number of studies done on the covalent modification of RBC with PEG, or PEG-
derivatives, suggests that the immunocamouflage of intact cells significantly reduces the …

BACKGROUND: Pegylation of red blood cells (RBCs) has been the primary focus of
research on the immunocamouflage of cell. The aim of this study was to demonstrate …

Background: Previous studies suggest that antibody engagement of red blood cells (RBCs)
can result in the actual loss of detectable target antigen in the setting of autoimmune …

Blood banks require a sensitive, specific, and efficient method to detect clinically significant
RBC antibodies. Solid phase antibody screening methods are popular due to high sensitivity …

BACKGROUND: Polyethylene glycol (PEG) has been shown to potentiate antigen‐antibody
reactions. STUDY DESIGN AND METHODS: To investigate the utility of PEG in …

B ackg ro und Blood group antigens and their significance for bl ood t ra nsfusion Blood
group antigens are polymorphisms in pro tein or carbohy d rate molecules on the surface of …

BACKGROUND: Today, blood group antigens are a strong barrier of safe transfusion. We
evaluated the change of agglutinability of antibody to RBC surface antigen before and after …

For quantification of the number of molecules of IgG anti-D bound to RBC, a combination of
flow cytometry plus Sol-ELISA was found more accurate than Sol-ELISA alone. However …