ABSTRACT INTRODUCTION: Heparin is a common anticoagulant prescribed to many heart
and surgical patients. These patients may develop antibodies to platelet factor 4 (PF4) and …

Objectives The aims of the study were to perform an instrument validation of the HemosIL
HIT-Ab (PF4-H) Assay and to compare the sensitivities and specificities of the three HIT tests …

Heparin-induced thrombocytopenia (HIT) is a life-threatening adverse reaction to heparin
that must be identified quickly to determine appropriate anticoagulant therapy strategies …

Introduction: Heparin-induced thrombocytopenia (HIT) is a potentially life-threatening
condition that could occur following exposure to heparin. Accurate and timely diagnosis is …

Background Functional platelet activation assays, such as the serotonin release assay
(SRA), are the gold standard for the diagnosis of heparin‐induced thrombocytopenia (HIT) …

BACKGROUND: Heparin-induced thrombocytopenia (HIT) is an adverse complication of
unfractionated and low molecular weight heparin caused by antibodies recognizing platelet …

Introduction Heparin-induced thrombocytopenia (HIT) is a potentially fatal, thrombotic
complication of heparin therapy mediated by antibodies to complexes between platelet …

Background: Heparin induced thrombocytopenia (HIT) is a life-threatening complication of
heparin exposure. It is characterized by the production of heparin-platelet factor 4 (PF4) …

Background Anecdotal reports suggest that the correlation between heparin/platelet factor 4
(PF4) antibody assays for the diagnosis of heparin-induced thrombocytopenia (HIT) is …

Abstract Background The PIFA PLUSS PF4 Rapid Assay (PIFA) is a rapid screening test
used for the diagnosis of heparin-induced thrombocytopenia (HIT). Objective To determine …