Objective: This review describes and discusses the different types of factors assays used in
the clinical laboratory for the diagnosis, as well as during therapeutic management, of …

From the early days of haemophilia therapy, measurements of factor VIII and factor IX, both
in patients samples and in therapeutic materials, have played a crucial role in the …

From the early days of haemophilia therapy, laboratory measurements have played a crucial
role in the development and control of optimal treatment regimens. In particular, the …

The treatment of a patient with a factor VIII (FVIII) deficiency can be complicated. The
mainstay of therapy is factor replacement. Replacement therapy can be given …

Accurate measurement of clotting factors VIII (FVIII) or IX (FIX) is vital for comprehensive
diagnosis and management of patients with hemophilia A or B. The one-stage activated …

Six one stage methods and one two stage method were tested for precision and
reproducibility. With each method twenty calibration curves of normal plasma and two lots of …

Factor VIII replacement therapy for patients with hemophilia A is conventionally monitored
using a plasma‐based factor VIII: C assay (a modified activated partial thromboplastin time …

Accurate measurement of clotting factors VIII (FVIII) or IX (FIX) is vital for comprehensive
diagnosis and management of patients with hemophilia A or B. The one-stage activated …

Introduction Management of hemophilia A has changed significantly in the past few years
with the expansion of new and/or modified products as treatment options. Unfortunately …

There are two assays suitable for the determination of the factor VIII activity in the patient's
plasma, both of which are commercially available and standardized: the onestage assay …