Biochemical and culture-based approaches to identification in the diagnostic microbiology laboratory

ST Altheide - American Society for Clinical Laboratory Science, 2020 - clsjournal.ascls.org
The late 1800s through the early 1900s saw the rapid development of growth media
containing various substrates, ie carbohydrates, to identify and differentiate microbes …

Matrix-assisted laser desorption ionization-time of flight mass spectrometry for the identification of bacterial and fungal isolates

ES Theel - Clinical Microbiology Newsletter, 2013 - Elsevier
Identification of bacterial and fungal isolates from clinical specimens has traditionally been
performed by examination of colony morphology and by biochemical characterization using …

Matrix-assisted laser desorption ionization–time of flight mass spectrometry: a fundamental shift in the routine practice of clinical microbiology

AE Clark, EJ Kaleta, A Arora… - Clinical microbiology …, 2013 - Am Soc Microbiol
Within the past decade, clinical microbiology laboratories experienced revolutionary
changes in the way in which microorganisms are identified, moving away from slow …

Pathology consultation on matrix-assisted laser desorption ionization–time of flight mass spectrometry for microbiology

C Wojewoda - American journal of clinical pathology, 2013 - academic.oup.com
Objectives: Traditional microbial identification methods are based on morphology (both
micro-and macroscopic) and biochemical tests that require long incubation periods and a …

Mass spectrometry in the clinical microbiology laboratory, part II: MALDI-TOF MS

PD Khot, MA Fisher - Clinical Microbiology Newsletter, 2012 - Elsevier
Recently, mass spectrometry methods have made significant inroads into the clinical
microbiology laboratory. This transformation has been driven largely by the success of …

Matrix-assisted laser desorption ionization–time of flight mass spectrometry in clinical microbiology

R Patel - Clinical infectious diseases, 2013 - academic.oup.com
Despite widespread application of nucleic acid diagnostics, cultures remain integral in
modern laboratories. Because cultures detect a large number of organism types, it is unlikely …

Direct bacterial identification in positive blood cultures by use of two commercial matrix-assisted laser desorption ionization–time of flight mass spectrometry systems

JHK Chen, PL Ho, GSW Kwan, KKK She… - Journal of clinical …, 2013 - Am Soc Microbiol
Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF
MS) for the identification of bacteria and fungi was recently introduced in microbiology …

Use of the MALDI BioTyper system with MALDI–TOF mass spectrometry for rapid identification of microorganisms

K Sogawa, M Watanabe, K Sato, S Segawa… - Analytical and …, 2011 - Springer
In a clinical diagnosis microbiology laboratory, the current method of identifying bacterial
isolates is based mainly on phenotypic characteristics, for example growth pattern on …

Assessment of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) for accurate bacterial identification in clinical labs

M Abdel-Rahman, MS Azab, M Meibed… - American Journal of …, 2020 - academic.oup.com
Abstract Introduction/Objective On behalf of the diagnostic Medical Laboratory rapid, and
accurate identification of bacteria with their one-to-one anti-microbial susceptibility outlines …

Effects of solid-medium type on routine identification of bacterial isolates by use of matrix-assisted laser desorption ionization–time of flight mass spectrometry

NW Anderson, BW Buchan, KM Riebe… - Journal of clinical …, 2012 - Am Soc Microbiol
Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF
MS) is a rapid method for the identification of bacteria. Factors that may alter protein profiles …