Next Generation Sequencing (NGS)-based assays have recently entered the realm of the
clinical microbiology laboratory9s capacity, providing an exciting potential for improvement …

Background Metagenomic next-generation sequencing (mNGS) for pathogen detection is
becoming increasingly available as a method to identify pathogens in cases of suspected …

Rapid and sensitive diagnostic strategies are necessary for patient care and public health.
Most of the current conventional microbiological assays detect only a restricted panel of …

Metagenomic next-generation sequencing (mNGS) is increasingly being applied in clinical
laboratories for unbiased culture-independent diagnosis. Whether it can be a next routine …

Context.—Metagenomic sequencing can be used for detection of any pathogens using
unbiased, shotgun next-generation sequencing (NGS), without the need for sequence …

The application of sequencing technology is shifting from research to clinical laboratories
owing to rapid technological developments and substantially reduced costs. However …

Agnostic metagenomic next-generation sequencing (mNGS) has emerged as a promising
single, universal pathogen detection method for infectious disease diagnostics. This …

The development of mNGS assays for pathogen detection has allowed for the diagnosis of
infections from rare and unexpected pathogens in several clinical cases. The broad nature …

Identification of causative pathogens in infectious disease is a critical component of health
care, as infectious diseases continue to be a leading cause of mortality and morbidity …

Infectious diseases have always been a difficult clinical problem, especially severe
infections and those infections of unknown origin. The invention of a new detection method …