Increasing rates of antimicrobial resistance is a public health crisis. The emergence of
resistant pathogens is multi-factorial but is at least partially due to inappropriate antibiotic …

Whole-Genome Sequencing for Rapid Susceptibility Testing of M. tuberculosis | NEJM Skip to
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Whole genome sequencing (WGS) can provide a comprehensive analysis of Mycobacterium
tuberculosis mutations that cause resistance to anti-tuberculosis drugs. With the deployment …

Routine whole genome sequencing (WGS) of pathogens is becoming more feasible as
sequencing costs decrease and access to benchtop sequencing equipment and …

Tuberculosis (TB) is a global infectious threat that is intensified by an increasing incidence of
highly drug-resistant disease. Whole-genome sequencing (WGS) studies of Mycobacterium …

Objectives We conducted a systematic review to determine the diagnostic accuracy of whole
genome sequencing (WGS) of Mycobacterium tuberculosis for the detection of resistance to …

Whole genome sequencing (WGS) can help to relate Mycobacterium tuberculosis genomes
to one another to assess genetic relatedness and infer the likelihood of transmission …

Whole-genome sequencing (WGS) can predict drug resistance and antimicrobial
susceptibility in Mycobacterium tuberculosis complex (MTBC) and has shown promise in …

Mycobacterium tuberculosis. We agree that whole-genome sequencing holds great promise
for the rapid diagnosis of drug-resistant tuberculosis, and acknowledge that genetic testing …

Use of whole-genome sequencing (WGS) for routine mycobacterial species identification
and drug susceptibility testing (DST) is becoming a reality. We compared the performances …