T regulatory (Treg) cells represent a unique subset of T lymphocytes. Although they
represent a small fraction of circulating T cells (< 10%) they are increasingly implicated in …

Abstract Regulatory CD4+ T (Treg) cells are comprised of a heterogeneous population of
cells that play a vital role in suppressing inflammation and maintaining immune tolerance …

Because of their potent suppressive capacity and critical role in the normal function of the
human immune system, T regulatory cells (Tregs) have long been considered candidates for …

Regulatory CD4+ T cells (Tregs) have become increasingly appreciated in their role of
facilitating immunological tolerance during homeostasis and during the diseased state. A …

Regulatory T (Treg)-cell populations have been identified in a number of disease models. In
this review we focus on the role of naturally occurring Treg cells in the control of intestinal …

The induction of antigen-specific unresponsiveness or tolerance is critical for the prevention
of autoimmunity and maintenance of immune homeostasis. The presence of regulatory T …

Regulatory T cells (Tregs) are central to the maintenance of self-tolerance and tissue
homeostasis. Markers commonly used to define human Tregs in the research setting include …

Regulatory T cells (Treg cells) have a central role in the maintenance of intestinal
homeostasis by restraining inappropriate immune responses in the healthy gut. Although …

Autoimmune diseases afflict approximately 5% of the population and reflect a failure in the
immune system to discriminate between self and non‐self resulting in the breakdown of self …

The discovery of FOXP3+ regulatory T (Treg) cells as a distinct cell lineage with a central
role in regulating immune responses provided a deeper understanding of self-tolerance …