PT - JOURNAL ARTICLE AU - Greiner, Katherine AU - Bettencourt, Joseph AU - Semolic, Carole TI - Strongyloidiasis: A Review and Update by Case Example AID - 10.29074/ascls.21.2.82 DP - 2008 Apr 01 TA - American Society for Clinical Laboratory Science PG - 82--88 VI - 21 IP - 2 4099 - http://hwmaint.clsjournal.ascls.org/content/21/2/82.short 4100 - http://hwmaint.clsjournal.ascls.org/content/21/2/82.full SO - Clin Lab Sci2008 Apr 01; 21 AB - A 77-year-old female immigrant from South America presented with epigastric pain, diarrhea, gastrointestinal bleeding, malabsorption, and acid reflux disorder. A gastroduodenoscopy, performed to assess for peptic ulcer disease, revealed parasitic larvae in the duodenal mucosa which were subsequently identified as Strongyloides stercoralis rhabditiform larvae. Anti-helminthic therapy was initiated to resolve infection.OBJECTIVES: Review the pathogenesis, diagnosis and treatment of strongyloidiasis; alert laboratory professionals to the importance of early detection of Strongyloides stercoralis in specimens from immigrants at risk and immunodeficient patients to reduce morbidity and mortality.ABBREVIATIONS: AIDS = acquired immunodeficiency syndrome; EIA = enzyme immunoassay; HIV = human immunodeficiency virus; HTLV-1 = human T-cell lymphotropic virus type 1; IgE = immunoglobulin E; IgG = immunoglobulin G.