PT  - JOURNAL ARTICLE
AU  - Liddell, Patty W.
AU  - Sparks, Mary Jean
TI  - Murine Typhus: Endemic Rickettsia in Southwest Texas
AID  - 10.29074/ascls.25.2.81
DP  - 2012 Apr 01
TA  - American Society for Clinical Laboratory Science
PG  - 81--87
VI  - 25
IP  - 2
4099  - http://hwmaint.clsjournal.ascls.org/content/25/2/81.short
4100  - http://hwmaint.clsjournal.ascls.org/content/25/2/81.full
SO  - Clin Lab Sci2012 Apr 01; 25
AB  - Murine Typhus is a zoonosis caused by the organism Rickettsia typhi and is transmitted to humans by fleas. It is endemic in several areas of Texas, California and Hawaii where the vector is supported predominantly by rodents in addition to opossums, domestic and feral cats and domestic dogs. We present a typical case in an adult from Corpus Christi, located in one of the four endemic areas in Texas. Included is an overview of the organism's pathogenicity and our host responses, both influencing the milder clinical course seen with this species of Rickettsia.ABBREVIATIONS: PCR – Polymerase Chain Reaction, DDT – dichlorodiphenyltrichloroethane, CDC – Centers for Disease Controland Prevention, INF – Interferon, TNF – Tumor Necrosis Factor, NK – Natural Killer Cell, LCMV- Lymphocytic Choriomeningitis Virus, CMV - Cytomegalovirus