PT - JOURNAL ARTICLE AU - Montoya, Isaac D. TI - The Pathology of Alcohol Use and Abuse AID - 10.29074/ascls.26.1.15 DP - 2013 Jan 01 TA - American Society for Clinical Laboratory Science PG - 15--22 VI - 26 IP - 1 4099 - http://hwmaint.clsjournal.ascls.org/content/26/1/15.short 4100 - http://hwmaint.clsjournal.ascls.org/content/26/1/15.full SO - Clin Lab Sci2013 Jan 01; 26 AB - Alcohol is the most widely abused substance in the United States and its pathology is responsible for more pathological conditions than all other forms of drug use combined.1 Alcohol dependence is associated with a number of adverse individual and societal consequences2,3 and high rates of morbidity and mortality.4 Alcohol use and abuse have a significant pathological effect on the brain, fetus, liver, heart, pancreas, and immune system.2 Cancer risks have also been attributed to alcohol use and abuse.5 Assessing acute and chronic alcohol consumption is critical to effective treatment but unfortunately currently available clinical laboratory testing procedures lack the ability to inform alcohol treatment providers about use and abuse.6ABBREVIATIONS: DSM-IV-Diagnostic and Statistical Manual of Mental Disorders, FAS-fetal alcohol syndrome, HDL-high density lipoprotein