PT - JOURNAL ARTICLE AU - Delost, Maria E. AU - Nadder, Teresa S. TI - Guidelines for Initiating a Research Agenda: Topic Selection and Evidence of Impact AID - 10.29074/ascls.27.4.231 DP - 2014 Oct 01 TA - American Society for Clinical Laboratory Science PG - 231--236 VI - 27 IP - 4 4099 - http://hwmaint.clsjournal.ascls.org/content/27/4/231.short 4100 - http://hwmaint.clsjournal.ascls.org/content/27/4/231.full SO - Clin Lab Sci2014 Oct 01; 27 AB - Describe factors portending significance and professional impact of potential research.Identify knowledge and practice gaps leading to formulation of specific, meaningful hypotheses and research questions.Apply rules related to informed consent and Institutional Review Board research approval.Describe elements of the research budget and budgeting process.The focus on scholarly productivity as an outcome measure for performance evaluations of personnel and/or units and benchmarking purposes is increasing in both the academic and clinical settings. This article presents avenues for identifying achievable research projects in both the academic and clinical settings. Factors for consideration when selecting a project include its significance or impact on the profession, feasibility for implementing the project, and ethical issues related to human subjects protection. A review of the literature is essential for identifying gaps in knowledge and for constructing the hypothesis or research question. Decisions concerning IRB submission, budget allocation, and collection of data must also be considered before implementation of the research design.ABBREVIATIONS: DV- Dependent variable, IRB - Institutional Review Board, IV - Independent variable, NIH - National Institute of Health, ORI - Federal Office of Research Integrity