PT - JOURNAL ARTICLE AU - Sturgill, Shauna M.M. AU - Gillard, Laurie TI - Managing Massive Transfusions in diverse Patient Populations in a Non-Metropolitan Area AID - 10.29074/ascls.30.4.258 DP - 2017 Oct 01 TA - American Society for Clinical Laboratory Science PG - 258--262 VI - 30 IP - 4 4099 - http://hwmaint.clsjournal.ascls.org/content/30/4/258.short 4100 - http://hwmaint.clsjournal.ascls.org/content/30/4/258.full SO - Clin Lab Sci2017 Oct 01; 30 AB - Compare and contrast massive transfusion protocols for adults, obstetrical, and pediatric patients.Discuss the complications of massive transfusions for each patient population.List the pharmacological agents that can be useful when a massive hemorrhage is suspected.Define critical access facilityMassive transfusion protocols have been developed to provide the best patient outcomes by administering the correct ratio of blood components and pharmacological agents available in today's market. Adults, obstetrical, and pediatric patients all have different needs during a massive hemorrhage. Patient outcomes, utilization of resources in a cost-effective manner, and education can all impact how this is accomplished. Through a literature review, this article outlines assesses the presence (or absence) of standard massive transfusion protocols for different patient populations in non-metropolitan areas where resources such as blood components can be difficult to obtain.ABBREVIATIONS: AABB – organization formerly known as the American Association of Blood Banks), RBCs - packed red blood cells, APTT - activated partial thromboplastin time, FDA - Food and Drug Administration, FFP - fresh frozen plasma, TRALI - transfusion acquired acute lung injury, TACO - transfusion associated circulatory overload, TXA - Tranexamic acid, rVIIa - Recombinant factor VIIa, PCCs - Prothrombin Complex Concentrates, PPH - postpartum hemorrhage