RT Journal Article
SR Electronic
T1 Past, Present and Future Options in the Treatment of Hemophilia A
JF American Society for Clinical Laboratory Science
JO Clin Lab Sci
FD American Society of Chemistry and Laboratory Science
SP ascls.118.001032
DO 10.29074/ascls.118.001032
A1 Castellone, Donna D
YR 2019
UL http://hwmaint.clsjournal.ascls.org/content/early/2019/10/26/ascls.118.001032.abstract
AB Patients who present with hemophilia A require treatment to replace low levels of Factor VIII (FVIII). Intervention can either be on demand or prophylactically. The goal of therapy is to prevent joint bleeds that lead to permanent damage. The progression of therapy in hemophilia A has provided patients with options resulting in a greatly improved quality of life. The newest development of gene therapy, to replace FVIII, may be the answer to cure this disease. This review provides a historical account of the treatment for hemophilia A as well as current available treatment options.