PT  - JOURNAL ARTICLE
AU  - Castellone, Donna D.
TI  - Past, Present, and Future Options in the Treatment of Hemophilia A
AID  - 10.29074/ascls.2018001032
DP  - 2019 Jan 01
TA  - American Society for Clinical Laboratory Science
PG  - 36--42
VI  - 32
IP  - 1
4099  - http://hwmaint.clsjournal.ascls.org/content/32/1/36.short
4100  - http://hwmaint.clsjournal.ascls.org/content/32/1/36.full
SO  - Clin Lab Sci2019 Jan 01; 32
AB  - Patients who present with hemophilia A require treatment to replace low levels of factor VIII (FVIII). Intervention can either be on-demand or prophylactic. The goal of therapy is to prevent joint bleeds that lead to permanent damage. The progression of therapy in hemophilia A has provided patients with options that result in a greatly improved quality of life. The newest development of gene therapy, a replacement for FVIII, may be the answer to cure this disorder. This review provides a historical account of the treatment of hemophilia A as well as current available treatment options.