PT  - JOURNAL ARTICLE
AU  - Dubansky, Brooke
AU  - Lewis, Sally
AU  - Telgenhoff, Dale
TI  - Classification and Histological Characteristics of Colorectal Cancer
AID  - 10.29074/ascls.2022003206
DP  - 2024 Sep 18
TA  - American Society for Clinical Laboratory Science
4099  - http://hwmaint.clsjournal.ascls.org/content/early/2024/09/18/ascls.2022003206.short
4100  - http://hwmaint.clsjournal.ascls.org/content/early/2024/09/18/ascls.2022003206.full
AB  - Classification and staging of recognized colorectal cancer subtypes are based on histological characteristics of the lesion and predictable changes in morphology. Adenocarcinoma arising from adenomatous polyps is the most common type of colorectal cancer. The histological progression from benign, non-neoplastic polyps to invasive neoplastic adenocarcinoma is, in many cases, correlated with specific molecular aberrations. This review describes the classification, histological characteristics, and progression of non-neoplastic, as well as benign and malignant neoplastic, colorectal lesions.