RT Journal Article
SR Electronic
T1 Classification and Histological Characteristics of Colorectal Cancer
JF American Society for Clinical Laboratory Science
JO Clin Lab Sci
FD American Society of Chemistry and Laboratory Science
DO 10.29074/ascls.2022003206
A1 Dubansky, Brooke
A1 Lewis, Sally
A1 Telgenhoff, Dale
YR 2024
UL http://hwmaint.clsjournal.ascls.org/content/early/2024/09/18/ascls.2022003206.abstract
AB Classification and staging of recognized colorectal cancer subtypes are based on histological characteristics of the lesion and predictable changes in morphology. Adenocarcinoma arising from adenomatous polyps is the most common type of colorectal cancer. The histological progression from benign, non-neoplastic polyps to invasive neoplastic adenocarcinoma is, in many cases, correlated with specific molecular aberrations. This review describes the classification, histological characteristics, and progression of non-neoplastic, as well as benign and malignant neoplastic, colorectal lesions.