<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vigil, Alexis</style></author><author><style face="normal" font="default" size="100%">Poulson, Taylor</style></author><author><style face="normal" font="default" size="100%">James, Oakley</style></author><author><style face="normal" font="default" size="100%">Rhees, Justin</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Blood Group Variants in an Egyptian Individual: A Case Study</style></title><secondary-title><style face="normal" font="default" size="100%">American Society for Clinical Laboratory Science</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2026</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2026-03-27 00:00:00</style></date></pub-dates></dates><doi><style  face="normal" font="default" size="100%">10.29074/ascls.2025003302</style></doi><volume><style face="normal" font="default" size="100%"></style></volume><issue><style face="normal" font="default" size="100%"></style></issue><abstract><style  face="normal" font="default" size="100%">An ABO discrepancy was detected in the teaching laboratory of a medical laboratory sciences (MLS) program when a student performed a type and antibody detect test (ADT) on their own blood specimen as part of an educational exercise. Following the initial results, an institutional review board (IRB) application was submitted and approved to further investigate the discrepancy (IRB-AY23-24-299). Subsequent serologic and molecular analyses revealed the presence of additional rare blood group alleles. The participant was found to have the rare A2B blood type with anti-A1 antibodies, a partial c antigen, and the GATA-box silencing mutation, contributing to the limited literature on blood group diversity in the student’s Egyptian ancestry.Managing blood transfusion in individuals with rare blood types presents unique challenges. Individuals exhibiting certain ABO discrepancies can complicate compatibility testing and increase the risk of hemolytic transfusion reactions unless they are accurately detected and the underlying cause identified.1 Additionally, inheritance of genetic variants, including partial c antigen expression, can lead to the formation of alloantibodies that complicate the acquisition of compatible blood. This case study highlights the critical role of combining serologic and molecular testing in identifying blood group genetic variants, underscores the value of hands-on learning in MLS programs, and demonstrates how educational laboratory activities can lead to clinically significant discoveries.A2B With Anti-A1 AntibodiesBlood group discrepancies due to ABO subtypes can complicate pretransfusion testing.1⇓⇓⇓-5 These discrepancies may lead to delays in care because of the need for additional investigation and an increased risk of adverse transfusion reactions.6 For instance, individuals with the A2B subtype may produce anti-A1 antibodies, which can contribute to these challenges.7 The AB blood type in the Egyptian population has been reported to occur in 9.74% of individuals.8 It is estimated that 22% to …</style></abstract></record></records></xml>