Table 3.

Demographics and percent LINE-1 methylation

Descriptor	Number of Cases n = 65	LINE-1 CpG Site 1	LINE-1 CpG Site 2	LINE-1 CpG Site 3	LINE-1 Average
Age (range)
<60 years (44–59)	25	92.8	55.4	55.9	67.6
≥60 years (60–85)	40	93.5	59.1	60.6	71.1
		P = .707	P = .149	P = .016	P = .105
Gender
Female	37	93.8	57.9	57.9	69.8
Male	28	92.5	58.0	59.5	70.0
		P = .489	P = .943	P = .422	P = .923
Race
African American	28	94.6	59.8	59.7	71.4
Caucasian	27	92.8	57.8	59.5	70.0
Other^a	10	89.2	51.0	54.4	64.9
		P = .330	P = .322	P = .931	P = .451
Smoking history
Yes	23	92.2	57.4	58.5	69.4
No	42	93.8	58.2	58.7	70.2
		P = .563	P = .745	P = .963	P = .726
Polyp location
Distal	24	91.4	56.5	57.6	68.5
Proximal	38	94.8	59.1	59.4	71.1
Mixed^b	3	86.0	53.3	56.7	65.3
		P = .064	P = .157	P = .400	P = .121
Polyp size
≤5 mm	32	94.3	59.6	60.3	71.4
6–9 mm	24	91.3	55.0	55.7	67.3
Mixed^b	9	91.3	55.8	58.4	68.5
		P = .127	P = .013	P = .020	P = .014
Metachronous tumors
No	35	89.2	52.6	52.7	64.8
Yes	30	97.9	64.1	65.5	75.8
		P < .001	P < .001	P < .001	P < .001

↵a Other included 3 Asian, 6 Hispanic, and 1 unknown.
↵b Cases in which multiple polyps were found that included both categories of size or location were excluded.