Average percentage of therapeutic INRs before and after diagnostic management implementation
| Therapeutic Range | Average % of Therapeutic INRs Pre-DMT | Average % of Therapeutic INRs Post-DMT | t Value | df | Sig. (2-Tailed) P < .05 |
|---|---|---|---|---|---|
| Target therapeutic range (2–3) or (2.5–3.5) | 61.99 | 73.58 | −2.24 | 49 | .030 |
| Expanded therapeutic (±0.2 INR units) | 72.07 | 83.78 | −2.73 | 49 | .009 |
| Expanded therapeutic (±0.3 INR units) | 75.55 | 86.2 | −2.74 | 49 | .009 |
Paired-sample t tests were used to test the hypothesis using SPSS version 22. There was a statistically significant increase in the average percentage of therapeutic INRs for both the target and expanded therapeutic ranges (±0.2 and ±0.3 INR units). Cutoff values for the expanded therapeutic range (±0.2 INR units) were 1.8–3.2 for an INR goal of 2–3 and 2.3–3.7 for an INR goal of 2.5–3.5.3 Cutoff values for the expanded therapeutic range (±0.3 INR units) were 1.7–3.3 for an INR goal of 2–3 and 2.2–3.8 for an INR goal of 2.5–3.5.25 Abbreviations: df, degrees of freedom; DMT, diagnostic management team; INR, international normalized ratio.