Number of therapeutic INRs in the target and expanded therapeutic ranges
| Therapeutic Range | No. of Therapeutic INRs Pre-DMT | No. of Therapeutic INRs Post-DMT | t Value | df | P Value (2-Tailed) |
|---|---|---|---|---|---|
| Target therapeutic range (2–3) or (2.5–3.5) | 107 | 157 | −3.796 | 49 | <.001 |
| Expanded therapeutic (±0.2 INR units) | 131 | 191 | −3.866 | 49 | <.001 |
| Expanded therapeutic (±0.3 INR units) | 141 | 201 | −3.588 | 49 | .001 |
Data were analyzed with paired-sample t tests using SPSS version 22. Cutoff values for the expanded therapeutic range (±0.2 INR units) were 1.8–3.2 for an INR goal of 2–3 and 2.3–3.7 for an INR goal of 2.5–3.5.3 Cutoff values for the expanded therapeutic range (±0.3 INR units) were 1.7–3.3 for an INR goal of 2–3 and 2.2–3.8 for an INR goal of 2.5–3.5.25 Abbreviations: df, degrees of freedom; DMT, diagnostic management team; INR, international normalized ratio; no., number.