Hemoglobin, total bilirubin, and treatment notes
| Date | Hgb (mg/dL) | T. Bili (mg/dL) | Fibrinogen (mg/dL) | D-Dimer (ug/ml) | Treatment Notes |
|---|---|---|---|---|---|
| 12/11/20 | nt | nt | nt | nt | COVID-19 test positive |
| 12/14/20 | 10.1 | 2.0 | nt | nt | Pancytopenia; elevated hemolysis indices |
| 12/19/20 | 6.8 | 3.1 | 505 | 0.96 | Hospital admission |
| 12/20/20 | 5.6 | 5.0 | 454 | >20 | 1 unit (Rh, Kell matched) caused exacerbation of hemolysis triggered by transfusion reaction; dexamethasone; enoxaparin |
| 12/21/20 | 3.9 | 4.7 | 433 | >20 | 1 unit phenotypically matched, irradiated, washed, and infused over 8 hours; dexamethasone; enoxaparin |
| 12/22/20 | 5.2 | 2.8 | nt | 4.72 | No transfusion; dexamethasone; IVIG; rivaroxaban |
| 12/23/20 | 4.9 | 2.5 | 419 | 2.02 | No transfusion; dexamethasone; EPO; IVIG; rivaroxaban |
| 12/24/20 | 4.5 | 4.4 | nt | 1.68 | 1 unit phenotypically matched, irradiated, and washed infused over 8 hours; EPO; IVIG; rivaroxaban |
| 12/25/20 | 4.4 | 5.3 | 504 | 1.88 | 1 unit phenotypically matched, irradiated, and washed infused over 8 hours; prednisone; EPO; rivaroxaban |
| 12/26/20 | 4.0 | 4.5 | 515 | 1.59 | 1 unit phenotypically matched, irradiated, and washed infused over 8 hours; prednisone; EPO; rivaroxaban |
| 12/27/20 | 4.0 | 4.5 | 536 | 1.27 | 1.5 units phenotypically matched, irradiated, and washed infused over 8 hours; prednisone; EPO; rivaroxaban; discontinued participation in the clinical study |
| 12/28/20 | 6.1 | 4.4 | 518 | 1.04 | 2.5 units phenotypically matched, irradiated, and washed infused at a slow rate; prednisone; EPO; rivaroxaban |
| 12/29/20 | 7.3 | 2.5 | nt | nt | 1 unit phenotypically matched, irradiated, and washed infused over 8 hours; prednisone; EPO; rivaroxaban |
| 12/30/20 | 7.3 | 2.5 | nt | 2.21 | Prednisone; EPO; rivaroxaban |
| 12/31/20 | 7.4 | 2.4 | nt | nt | Prednisone; EPO; COVID-19 PCR test negative; rivaroxaban |
| 1/1/21 | 8.1 | 2.4 | nt | 1.49 | Discharged; maintained on 50 mg daily prednisone |
Patient’s hemoglobin, T. Bili, fibrinogen, D-dimer, and daily treatment notes following COVID-19 infection and hospitalization are shown in a chronological order. Dexamethasone, 40 mg; enoxaparin, 40 mg; EPO, epoetin alfa 40 000 units/mL; Hgb, hemoglobin; IVIG, immune globulin 500 mg/kg infusion; nt, not tested; PCR, polymerase chain reaction; prednisone, 110 mg; rivaroxaban, 10 mg; T. Bili, total bilirubin.