Background At least 25 % of adults admitted to intensive care units (ICU) in the United States
have an overweight, obese or morbidly obese body mass index (BMI). The effect of BMI on …

Background Procalcitonin (PCT)-guided antibiotic discontinuation appears to decrease
antibiotic use in critically ill patients, but its impact on survival remains less certain. Methods We …

This article has been corrected. To see what has changed, please read the Letter to the
Editor and the authors' response . The original version (PDF) is appended to this article as a …

Objective: Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome
(TB-IRIS) is a frequent complication of antiretroviral therapy in resource-limited countries. …

Background. Tuberculosis immune reconstitution inflammatory syndrome (IRIS) is a common
cause of deterioration in human immunodeficiency virus (HIV)–infected patients receiving …

Background. Paradoxical neurologic tuberculosis-associated immune reconstitution
inflammatory syndrome (TB-IRIS) is a potentially life-threatening condition that occurs within 3 …

Background Mycobacterium tuberculosis is a common, devastating cause of meningitis in
HIV-infected persons. Due to international rollout programs, access to antiretroviral therapy (…

Rationale: Tuberculosis-associated immune reconstitution inflammatory syndrome (TB–IRIS)
induced by combination antiretroviral therapy (cART) has been attributed to dysregulated …

Objectives: Observational studies suggest obesity is associated with sepsis survival, but
these studies are small, fail to adjust for key confounders, measure body mass index at …

The gastrointestinal (GI) tract is a major site of disease in HIV infection: almost half of HIV-infected
patients present with GI symptoms, and almost all patients develop GI complications. …