Maintaining a balance between bleeding and clotting has always been a challenge in treating
coagulation disorders. A perturbation in that balance can be associated with substantial …

Objectives: To develop reference ranges for platelet aggregation using the Multiplate analyzer
(Roche Diagnostics, Mannheim, Germany) in blood anticoagulated with sodium citrate (Na…

Quantification of inhibitory antibodies against infused factor VIII (FVIII) has an important role
in the management of patients with hemophilia A. This article summarizes results from the …

We evaluated the accuracy and precision of von Willebrand disease (vWD) testing performed
by up to 50 North American Specialty Coagulation Laboratories from 2004 through 2009, …

The treatment of a patient with a factor VIII (FVIII) deficiency can be complicated. The mainstay
of therapy is factor replacement. Replacement therapy can be given prophylactically, with …

Abstract 4730 Background: The ADVIA® 2120/2120i body fluid application is an in vitro
diagnostic test for the enumeration of the total nucleated cell (TNC) or white blood cell (WBC) …

Introduction Obtaining a reference interval ( RI ) is a challenge for any laboratory and becomes
more complicated in the coagulation laboratory due to testing on samples with limited …

Patients who present with hemophilia A require treatment to replace low levels of Factor VIII
(FVIII). Intervention can either be on demand or prophylactically. The goal of therapy is to …

Introduction: Differences in coagulation assay reagents may lead to variable results for
some extended-half-life (EHL) recombinant factor VIII (rFVIII) products, with the potential to …

When looking at the APTT and concentration of dabigatran, there is a curvilinear relationship
between the APTT and plasma concentration of dabigatran and other direct thrombin …