User profiles for Edward L. Chan

Edward KL Chan

Professor of Oral Biology, University of Florida
Verified email at ufl.edu
Cited by 30364

[HTML][HTML] AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

CY Chen, R Gherzi, SE Ong, EL Chan, R Raijmakers… - Cell, 2001 - cell.com
Inherently unstable mammalian mRNAs contain AU-rich elements (AREs) within their 3′
untranslated regions. Although found 15 years ago, the mechanism by which AREs dictate …

[HTML][HTML] Randomized, double-blind, placebo-controlled, global phase III trial of talimogene laherparepvec combined with pembrolizumab for advanced melanoma

…, JR Anderson, S Treichel, EL Chan… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
PURPOSE The combination of talimogene laherparepvec (T-VEC) and pembrolizumab
previously demonstrated an acceptable safety profile and an encouraging complete response …

Analysis of an exon 1 polymorphism of the B2 bradykinin receptor gene and its transcript in normal subjects and patients with C1 inhibitor deficiency

CC Lung, EL Chan, BL Zuraw - Journal of Allergy and Clinical Immunology, 1997 - Elsevier
The B2 bradykinin receptor (B2BKR) mediates most of the inflammatory actions ofbradykinin.
To evaluate its potential role in allergic diseases, we assessed the structure of the human …

A novel activating, germline JAK2 mutation, JAK2R564Q, causes familial essential thrombocytosis

…, ME Roh, MA Seeliger, EL Chan… - Blood, The Journal …, 2014 - ashpublications.org
Along with the most common mutation, JAK2V 617 F, several other acquired JAK2 mutations
have now been shown to contribute to the pathogenesis of myeloproliferative neoplasms (…

Comparison of Chemicon SimulFluor direct fluorescent antibody staining with cell culture and shell vial direct immunoperoxidase staining for detection of herpes …

EL Chan, K Brandt, GB Horsman - Clinical Diagnostic Laboratory …, 2001 - Am Soc Microbiol
A new rapid direct immunofluorescence assay, the SimulFluor direct fluorescent-antibody (DFA)
assay, which can simultaneously detect herpes simplex virus types 1 and 2 (HSV-1 and -…

Performance Characteristics of the Becton Dickinson ProbeTec System for Direct Detection of Chlamydia trachomatis and Neisseria gonorrhoeae in Male and …

EL Chan, K Brandt, K Olienus… - … of pathology & …, 2000 - meridian.allenpress.com
Objective.—The Becton Dickinson BDProbeTec ET System is a new semiautomated system
using strand displacement amplification technology that simultaneously amplifies and …

Determination of synergy by two methods with eight antimicrobial combinations against tobramycin-susceptible and tobramycin-resistant strains of Pseudomonas

EL Chan, RJ Zabransky - Diagnostic microbiology and infectious disease, 1987 - Elsevier
Eleven strains of tobramycin-susceptible Pseudomonas aeruginosa , 12 strains of
tobramycin-resistant P . aeruginosa , and 11 strains of P . maltophilia were tested against tobramycin …

A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. III. Comparative performance characteristics of …

…, EM Tan, JS Smolen, JS McDougal, EK l Chan… - The Journal of …, 2003 - jrheum.org
OBJECTIVE: To analyze the performance of different commercial enzyme immunoassay (EIA)
kits for measuring antinuclear antibodies (ANA) specific for dsDNA, SSB/La, Sm, and Scl-…

Combination of phosphorylated and truncated EGFR correlates with higher tumor and nodal stage in head and neck cancer

…, HL Zhao, LM Dong, MJ Hayman, EL Chan - Cancer …, 2010 - Taylor & Francis
Epidermal growth factor receptor (EGFR) is a target in head and neck cancer. High EGFR
expression and phosphorylated EGFR predicts poor survival in head and neck cancer patients…

Evaluation of fluorescence-based amplified fragment length polymorphism analysis for molecular typing in hospital epidemiology: comparison with pulsed-field gel …

NA Antonishyn, RR McDonald, EL Chan… - Journal of Clinical …, 2000 - Am Soc Microbiol
Fluorescence-based amplified fragment length polymorphism (fbAFLP) is a novel assay
based on the fluorescent analysis of an amplified subset of restriction fragments. The fbAFLP …