Background Somatic mutations have the potential to encode “non-self” immunogenic antigens.
We hypothesized that tumors with a large number of somatic mutations due to mismatch-…

The gastrointestinal (GI) tract is a major site of disease in HIV infection: almost half of HIV-infected
patients present with GI symptoms, and almost all patients develop GI complications. …

Thyroid cancer is the most common endocrine malignancy, and its incidence is rising in the
USA and other countries. Papillary and follicular thyroid carcinomas are the two most …

Background & Aims Gastric ischemia is infrequently reported in the medical literature and
under-recognized clinically and histopathologically. Various medical terms are used to …

Head and neck squamous cell carcinoma (HNSCC) is a major cause of morbidity and mortality,
and the alleviation thereof requires greater understanding of the pathobiologic behavior …

Gene expression profiling reveals elevated Notch1 mRNA expression in triple negative
breast cancers (TNBC), both basaloid and claudin-low subtypes. Notch ligands, Jagged1 and …

Muir-Torre syndrome (MTS) is a rare autosomal-dominant genodermatosis characterized by
sebaceous neoplasms and one or more visceral malignancies. Sebaceous tumors include …

Autoimmune metaplastic atrophic gastritis (AMAG) is a significant risk factor for pernicious
anemia and gastric neoplasia. Still, the histologic features of AMAG are frequently overlooked, …

Primary effusion lymphoma (PEL) is a distinct clinicopathologic entity associated with human
herpesvirus 8 (HHV8) infection that mostly affects patients with immunodeficiency. Primary …

As targeted therapies are superiorto standard chemotherapy in select patients, effective
predictive biomarkers are needed to identify patients who are more likely to respond to targeted …