Turnout gear provides protection against dermal exposure to contaminants during firefighting;
however, the level of protection is unknown. We explored the dermal contribution to the …

This report describes a previously uncharacterized occupational health hazard: work crew
exposures to respirable crystalline silica during hydraulic fracturing. Hydraulic fracturing …

Scaling of metabolic clearance values from liver microsomal data or recombinantly expressed
cytochrome P450 enzymes to predict human hepatic clearance requires knowledge of the …

In studies designed to simulate a clinical observation in which an individual became tolerant
to normally lethal doses of acetaminophen (APAP), mice were pretreated with increasing …

We briefly describe how toxicology can inform the discussion and debate of the merits of
hydraulic fracturing by providing information on the potential toxicity of the chemical and …

Exposure science is fundamental to the field of occupational safety and health. The measurement
of worker exposures to hazardous agents informs effective workplace risk mitigation …

We describe a fluorescent covalent microsphere immunoassay (FCMIA) method for the
simultaneous (multiplexed) measurement of immunoglobulin G (IgG) antibodies to 23 …

Exposure to pesticides is a major public health concern, because of the widespread distribution
of these compounds and their possible long term effects. Recently, organic farming has …

Recently, the Centers for Disease Control and Prevention reported an accurate, sensitive,
specific, reproducible, and quantitative enzyme-linked immunosorbent assay (ELISA) for …

The effect of acetaminophen (APAP) dose on the cytochrome P450s responsible for its
bioactivation was examined in control mice and mice treated with acetone to induce CYP2E1, or β…