The piwi family genes, which are defined by conserved PAZ and Piwi domains, play important
roles in stem cell self-renewal, RNA silencing, and translational regulation in various …

BACKGROUND: Anorectal malformations (ARM) are common congenital anomalies seen
throughout the world. Comparison of outcome data has been hindered because of confusion …

The transcription factor Sox9 is expressed in all chondroprogenitors and has an essential
role in chondrogenesis. Sox9 is also expressed in other tissues, including central nervous …

Intralesional injection of OK-432 (lyophilized incubation mixture of group AStreptococcus
pyogenes of human origin) is safe and effective therapy for lymphangioma. The authors …

Generation of left–right asymmetry is an integral part of the establishment of the vertebrate
body plan. Here we show that the Notch signaling pathway plays a primary role in the …

Intralesional injection of OK-432 was employed to treat 64 lymphangiomas between 1986
and 1992. This was used as primary therapy for 46 lesions (group A), as treatment following …

The mammalian olfactory neuroepithelium provides a unique system for understanding the
regulation of neurogenesis by adult neural stem cells. Recently, mouse horizontal basal cells …

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
with concerning phenotypic mutations is of public health interest. Genomic surveillance is …

To avoid surgery-related complications, intralesional OK-432 therapy was used in 23 patients
with unresectable lymphangiomas (1986 through 1989). Total or near total shrinkage of …

Of 37 patients with congenital choledochal dilatation, aged 8 days to 12 years, who had
undergone excision with Roux-en-Y hepaticojejunostomy, 26 patients could be analyzed for …