Background Human Hematopoietic Signal peptide-containing Secreted 1 (hHSS1) is a truly
novel protein, defining a new class of secreted factors. We have previously reported that …

The promise of adaptive cancer immunotherapy in treating highly malignant tumors such as
glioblastoma multiforme (GBM) can only be realized through expanding its benefits to more …

Background Cancer vaccines reproducibly cure laboratory animals and reveal encouraging
trends in brain tumor (glioma) patients. Identifying parameters governing beneficial vaccine-…

Glioblastoma multiforme (GBM) is a malignant neoplasm of the CNS with almost uniform
lethality. Even with standard-of-care treatments, the prognosis for patients remains dismal. GBM…

The novel nuclear protein nBMP2 is synthesized from the BMP2 gene by translational initiation
at an alternative start codon. We generated a targeted mutant mouse, nBmp2NLS tm , in …

Mitigating effects of aging on human health remains elusive because aging impacts multiple
systems simultaneously, and because experimental animals exhibit critical aging …

The incidence of autism spectrum disorders (ASD) and attention deficit hyperactivity disorder
(ADHD), which frequently co-occur, are both rising. The causes of ASD and ADHD remain …

Cerebral (Aβ) plaque and (pTau) tangle deposition are hallmarks of Alzheimers disease (AD),
yet are insufficient to confer complete AD-like neurodegeneration experimentally. Factors …

Cerebral (Aβ) plaque and (pTau) tangle deposition are hallmarks of Alzheimer’s disease (AD),
yet are insufficient to confer complete AD-like neurodegeneration experimentally. Factors …

One of the most important tests in the clinical laboratory is the Complete Blood Count, which
involves identifying the white blood cells in a patient’s blood. The respective counts of the …