1. Explain the difference between structural hemoglobin disorders and thalassemias, and
describe the types of mutations found in the structural disorders. 2. Describe globin gene …

DATA SOURCES: Current literature. DATA SYNTHESIS: Chronic myelocytic leukemia (CML)
was initially described in 1845 and is considered one of the first leukemias to be discovered…

The objectives of this review paper are to: Compare acute leukemia with chronic leukemia
and other forms of cancer. Review the pathophysiology and discuss the clinical and …

DATA SOURCES: Current literature DATA SYNTHESIS: Acute lymphoblastic leukemia (ALL)
is a stem cell disorder characterized by an overproduction of lymphoblasts in the bone …

The objective of this study was to develop a diagnostic testing method to detect HbS, distinguish
sickle cell homozygotes from heterozygotes, and overcome testing barriers encountered …

OBJECTIVE: The purpose of this study is to estimate the prevalence of sickle hemoglobin in
northern Haiti. DESIGN: Sickle cell testing occurred from 2002-2009. Blood samples from …

DATA SOURCES: Current literature. DATA SYNTHESIS: Chronic myelocytic leukemia (CML)
was initially described in 1845 and is considered one of the first leukemias discovered. …

… TIM R RANDOLPH … Tim R Randolph PhD MT(ASCP) CLS(NCA) is associate … Address for
Correspondence:Tim R Randolph MS MT(ASCP) CLS(NCA), associate professor, Department …

To identify the chromosomal translocation common in M3 and discuss its diagnostic use to:
Compare acute leukemia with chronic leukemia and other forms of cancer. Describe the …

OBJECTIVE: To develop a micro-erythrocyte sedimentation rate (ESR) system with potential
to be self-administered by patients at home using capillary blood. DESIGN: For each subject…