Motivation: Comparing two or more complex protein mixtures using liquid chromatography
mass spectrometry (LC-MS) requires multiple analysis steps to locate and quantitate natural …

Array-based comparative genomic hybridization (array-CGH) provides a high-throughput,
high-resolution method to measure relative changes in DNA copy number simultaneously at …

Background Mechanisms linking a proinflammatory diet to obesity remain under
investigation. The ability of diet to influence the gut microbiome (GM) in creating chronic low-grade …

Background: Oral cancer is the sixth most common cancer with a 5-year survival rate of
approximately 60%. Presently, there are no scientifically credible early detection techniques …

Purpose We have implemented a high throughput platform for quantitative analysis of serum
autoantibodies, which we have applied to lung cancer for discovery of novel antigens and …

Background Trimethylamine N-oxide (TMAO), a compound derived from diet and metabolism
by the gut microbiome, has been associated with several chronic diseases, although the …

Background: This report and a companion report describe a validation of the ability of serum
proteomic profiling via SELDI-TOF mass spectrometry to detect prostatic cancer. Details of …

Acute graft-versus-host disease (aGVHD) remains a major limitation of allogeneic stem cell
transplantation (SCT), and severe intestinal manifestation is the major cause of early mortality…

Background The gut microbiome may play a role in inflammation associated with type 2
diabetes (T2D) development. This cross-sectional study examined its relation with glycemic …

Chronic graft-versus-host disease (GVHD) commonly occurs after allogeneic hematopoietic
cell transplantation (HCT) despite standard prophylactic immune suppression. Intensified …